Effects of topical gallium maltolate (Gallixa^® skin cream) on complex regional pain syndrome (CRPS) in the right hand of a 54-year-old woman. Before treatment (A) the affected hand showed significant edema, was in pain, and had considerable loss of mobility. Following one month of treatment with topical gallium maltolate three times per day (B), the edema and pain were nearly eliminated and mobility was restored. The patient was taking oral prednisone during some of this time, so the effects of the two compounds cannot be separated, but previous use of prednisone and other treatments had not been successful. A surgical nerve block had been recommended, but was rendered unnecessary following treatment with topical gallium maltolate.